Each year, the editorial board of Current Therapeutic Research selects one article from the previous year that they feel exemplifies Dr. Ream's interest in randomized, controlled trials that try to accomplish important goals. Eligible studies are challenging clinical trials carried through with the highest-quality scientific methodology and analysis in the service of a worthwhile goal. The winning investigators receive a Waterford crystal globe and the thanks of everyone at the journal and its readers for their fine articles. The following are past recipients.

2009 Award:

Efficacy and Safety of Solifenacin Succinate 10 mg Once Daily: A Multicenter, Phase III, Randomized, Double-Blind, Placebo-Controlled, Parallel-Group Trial in Patients With Overactive Bladder
Chu et al.
[PDF]

2008 Award:

Effect of Equivalent Doses of Fentanyl, Sufentanil, and Remifentanil on the Incidence and Severity of Cough in Patients Undergoing Abdominal Surgery: A Prospective, Randomized, Double-Blind Study
J.C. Shen et al.
[PDF]

2007 Award:

Comparison of Dexmedetomidine and Midazolam for Monitored Anesthesia Care Combined with Tramadol via Patient-Controlled Analgesia in Endoscopic Nasal Surgery: A Prospective, Randomized, Double-Blind, Clinical Study.
Karaaslan et al.
[PDF]

2006 Award:

Effects of Combination Treatment with Policosanol and Omega-3 Fatty Acids on Platelet Aggregation: A Randomized, Double-Blind Clinical Study.
Castaño et al.
[PDF]

2005 Award:

Effects of Pentosan Polysulfate in Osteoarthritis of the Knees: A randomized, Double-Blind, Placebo-Controlled Pilot Study
P. Ghosh et al.
[PDF]

2004 Award:

Comparison of the Effects of Parecoxib and Diclofenac in Preemptive Analgesia: A Prospective, Randomized, Assessor-Blind, Single-Dose, Parallel-Group Study in Patients Undergoing Elective General Surgery
P. Bajaj et al.
[PDF]

2003 Award:

Intravenous Lysine Clonixinate for the Acute Treatment of Severe Migraine Attacks: A Double-Blind, Randomized, Placebo-Controlled Study
A.V. Krymchantowski and M.T.T. Silva
[PDF]

2002 Award:

Complete Results of the First Randomized, Placebo-Controlled Study of Bosentan, a Dual Endothelin Receptor Antagonist, in Pulmonary Arterial Hypertension
D.B. Badesch et al.
[PDF]

2001 Award:

A Double-Masked, Placebo-Controlled Polysomnographic Study of the Antitussive Effects of Helididine
R. Sergysels and G. Art
[PDF]

2000 Award:

Comparison of Oral Montelukast and Inhaled Cromolyn with Respect to Preference, Satisfaction, and Adherence: A Multicenter, Randomized, Open-Label, Crossover Study in Children with Mild to Moderate Persistent Asthma
B. Volovitz
[PDF]