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Mary Murphy (1943–2002)
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iii
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The emergence of rational therapeutics from the traditions of clinical practice
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Jeffrey L. Blurrier
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A1-A3
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Single-dose azithromycin for acute otitis media: A pharmacokinetic/pharmacodynamic rationale
Abstract: The pharmacokinetic (PK) and pharmacodynamic (PD) properties of the azalide azithromycin distinguish it from other antibiotics. The PK profile of azithromycin features high tissue-to-serum r...
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Constance D. Rothermel
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A4-A15
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A pilot study of single-dose azithromycin versus three-day azithromycin or single-dose ceftriaxone for uncomplicated acute otitis media in children
Abstract: Background: The pharmacokinetic profile of azithromycin supports its use as single-dose therapy for uncomplicated acute otitis media (AOM) in children. Objective: This study was designed to ...
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Adriano Arguedas,
Cecilia Loaiza,
Alexandra Perez,
Alvaro Gutierrez,
Marco Luis Herrera,
Constance D Rothermel
et al.
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A16-A29
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Single-dose (30 mg/kg) azithromycin compared with 10-day amoxicillin/clavulanate (45 mg/kg per day) for the treatment of uncomplicated acute otitis media
Abstract: Background: The long half-life of azithromycin allows for single-dose oral therapy for acute otitis media (AOM). Objective: This study was designed to compare the efficacy and safety of sing...
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Stan L. Block,
Antonio Arrieta,
Matthew Seibei,
Samuel McLinn,
Stephen Eppes,
Mary J. Murphy
et al.
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A30-A42
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